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A new hydroxylated nonaprenylhydroquinone from the Mediterranean marine sponge Sarcotragus spinosulus
Abed, C.; Legrave, N.; Dufies, M.; Robert, G.; Guérineau, V.; Vacelet, J.; Auberger, P.; Amade, P.; Mehiri, M. (2011). A new hydroxylated nonaprenylhydroquinone from the Mediterranean marine sponge Sarcotragus spinosulus. Mar. Drugs 9(7): 1210-1219.
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, more
Peer reviewed article  

Available in  Authors | Dataset 

    Sarcotragus spinosulus Schmidt, 1862 [WoRMS]
Author keywords
    Sponges; Sarcotragus spinosulus; marine natural products; hydroxylated polyprenylhydroquinone; bioactivity

Authors  Top | Dataset 
  • Abed, C.
  • Legrave, N.
  • Dufies, M.
  • Robert, G.
  • Guérineau, V.
  • Vacelet, J., more
  • Auberger, P.
  • Amade, P.
  • Mehiri, M.

    Chemical investigation of the Mediterranean sponge Sarcotragus spinosulus led to the isolation of a new hydroxylated nonaprenylhydroquinone, along with two known metabolites, hepta- and octaprenylhydroquinones. The structure of the new metabolite was assigned by extensive 1D and 2D NMR analyses and MS studies. The antileukemic effect of the three compounds towards the chronic myelogenous leukemia (CML) cells line K562 was also evaluated.

  • Linares, Cristina; Figuerola, Laura; Gómez-Gras, Daniel; Pagès-Escolà, Marta; Olvera, Àngela, Aubach, Àlex; Amate, Roger; Figuerola, Blanca; Kersting, Diego; Ledoux, Jean-Baptiste; López-Sanz, Àngel; López-Sendino, Paula; Medrano, Alba; Garrabou, Joaquim; (2020); CorMedNet- Distribution and demographic data of habitat-forming invertebrate species from Mediterranean coralligenous assemblages between 1882 and 2019, more

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