[ report an error in this record ] Mr Defoirdt, Tom ORCID ResearcherID Previous institutes (2)  Top | Publications | Project  Ghent University; Faculty of Bioscience Engineering; Department of Biotechnology; Center for Microbial Ecology and Technology (CMET), more Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Dierwetenschappen en Aquatische Ecologie; Laboratorium voor Aquacultuur en Artemia Reference Center (ARC), more Project  Top | Publications | Project  Disruption of quorum sensing in order to prevent and cure aquatic disease, more Publications (88)  Top | Publications | Project  A1 Publications (80) [show] Defoirdt, T. (2023). Indole signaling, a promising target to control vibriosis in aquaculture. Aquaculture 574: 739692. https://dx.doi.org/10.1016/j.aquaculture.2023.739692, more Zhang, S.; Van Haesebroeck, J.; Yang, Q.; Defoirdt, T. (2023). Indole-3-acetic acid increases the survival of brine shrimp challenged with vibrios belonging to the Harveyi clade. J. Fish Dis. 46(5): 477-486. https://dx.doi.org/10.1111/jfd.13759, more Zhang, S.; Yang, Q.; Eggermont, M.; Defoirdt, T. (2023). Quorum-sensing interference in vibrios. Reviews in Aquaculture 15(4): 1452-1466. https://dx.doi.org/10.1111/raq.12787, more Zhang, S.; Yang, Q.; Defoirdt, T. (2023). Halogenated indoles decrease the virulence of Vibrio campbellii in a gnotobiotic brine shrimp model. Microbiology Spectrum 10(5): 1-12. https://dx.doi.org/10.1128/spectrum.02689-22, more Gan, L.; Zheng, J.; Xu, W.-H.; Lin, J.; Liu, J.; Zhang, Y.; Wu, Z.; Lv, Z.; Jia, Y.; Guo, Q.; Chen, S.; Liu, C.; Defoirdt, T.; Qin, Q.; Liu, Y. (2022). Deciphering the virulent Vibrio harveyi causing spoilage in muscle of aquatic crustacean Litopenaeus vannamei. NPG Scientific Reports 12(1): 16296. https://dx.doi.org/10.1038/s41598-022-20565-1, more Islam, S.S.; Zhang, S.; Eggermont, M.; Bruto, M.; Le Roux, F.; Defoirdt, T. (2022). The impact of the multichannel quorum sensing systems of Vibrio tasmaniensis and Vibrio crassostreae on virulence towards blue mussel (Mytilus edulis) larvae. Aquaculture 547: 737414. https://dx.doi.org/10.1016/j.aquaculture.2021.737414, more Zhang, S.; Yang, Q.; Fu, S.; Janssen, C.R.; Eggermont, M.; Defoirdt, T. (2022). Indole decreases the virulence of the bivalve model pathogens Vibrio tasmaniensis LGP32 and Vibrio crassostreae J2-9. NPG Scientific Reports 12(1): 5749. https://dx.doi.org/10.1038/s41598-022-09799-1, more Zhang, S.; Yang, Q.; Defoirdt, T. (2022). Indole decreases the virulence of pathogenic vibrios belonging to the Harveyi clade. J. Appl. Microbiol. 132(1): 167-176. https://dx.doi.org/10.1111/jam.15227, more Zhang, S.; Yang, Q.; Defoirdt, T. (2022). Indole analogues decreasing the virulence of Vibrio campbellii towards brine shrimp larvae. Microbial biotechnology 15(12): 2917-2928. https://dx.doi.org/10.1111/1751-7915.14160, more Göing, S.; Gasperotti, A.F.; Yang, Q.; Defoirdt, T.; Jung, K. (2021). Insights into a pyruvate sensing and uptake system in Vibrio campbellii and its importance for virulence. J. Bacteriol. 203(20): e00296-21. https://dx.doi.org/10.1128/JB.00296-21, more Heyse, J.; Props, R.; Kongnuan, P.; De Schryver, P.; Rombaut, G.; Defoirdt, T.; Boon, N. (2021). Rearing water microbiomes in white leg shrimp (Litopenaeus vannamei) larviculture assemble stochastically and are influenced by the microbiomes of live feed products. Environ. Microbiol. 23(1): 281-298. https://hdl.handle.net/10.1111/1462-2920.15310, more Wang, Q.; Zhang, Y.; Yang, Q.; Fu, S.; Qu, B.; Defoirdt, T. (2021). One health pathogen surveillance demonstrated the dissemination of gut pathogens within the two coastal regions associated with intensive farming. Gut Pathogens 13(1): 47. https://dx.doi.org/10.1186/s13099-021-00442-4, more Eggermont, M.; Cornillie, P.; Dierick, M.; Adriaens, D.; Nevejan, N.; Bossier, P.; Van Den Broeck, W.; Sorgeloos, P.; Defoirdt, T.; Declercq, A.M. (2020). The blue mussel inside: 3D visualization and description of the vascular-related anatomy of Mytilus edulis to unravel hemolymph extraction. NPG Scientific Reports 10(1): 6773. https://hdl.handle.net/10.1038/s41598-020-62933-9, more Defoirdt, T. (2019). Amino acid–derived quorum sensing molecules controlling the virulence of vibrios (and beyond). PLoS Pathog. 15(7): e1007815. https://dx.doi.org/10.1371/journal.ppat.1007815, more Eggermont, M.; Cornillie, P.; Nevejan, N.; Bossier, P.; Dierick, M.; Adriaens, D.; Sorgeloos, P.; Defoirdt, T.; Declercq, A.M. (2019). Hemolymph extraction sites and 3d-visualization of the cardiovascular system and related structures of the blue mussel (Mytilus edulis). Isj-Invertebrate Survival Journal 16: 202-202, more Muthukrishnan, S.; Defoirdt, T.; Ina-Salwany, M.Y.; Yusoff, F.M.; Shariff, M.; Ismail, S.I.; Natrah, I. (2019). Vibrio parahaemolyticus and Vibrio harveyi causing Acute Hepatopancreatic Necrosis Disease (AHPND) in Penaeus vannamei (Boone, 1931) isolated from Malaysian shrimp ponds. Aquaculture 511: 734227. https://dx.doi.org/10.1016/j.aquaculture.2019.734227, more Noor, N.M.; Defoirdt, T.; Alipiah, N.; Karim, M.; Daud, H.; Natrah, I. (2019). Quorum sensing is required for full virulence of Vibrio campbellii towards tiger grouper (Epinephelus fuscoguttatus) larvae. J. Fish Dis. 42(4): 489-495. https://dx.doi.org/10.1111/jfd.12946, more De Bodt, J.; Defoirdt, T. (2018). Impact of the organic load on the efficacy of chlorine disinfection against acute hepatopancreatic necrosis disease-causing Vibrio parahaemolyticus. J. Fish Dis. 41(10): 1609-1612. https://dx.doi.org/10.1111/jfd.12866, more Defoirdt, T.; Anh, N.T.M.; De Schryver, P. (2018). Virulence-inhibitory activity of the degradation product 3-hydroxybutyrate explains the protective effect of poly-β-hydroxybutyrate against the major aquaculture pathogen Vibrio campbellii. NPG Scientific Reports 8: 7245. https://dx.doi.org/10.1038/s41598-018-25385-w, more Li, X.; Dierckens, K.; Bossier, P.; Defoirdt, T. (2018). The impact of quorum sensing on the virulence of Vibrio anguillarum towards gnotobiotic sea bass (Dicentrarchus labrax) larvae. Aquac. Res. 49(11): 3686-3689. https://dx.doi.org/10.1111/are.13821, more Defoirdt, T.; Vlaeminck, S.E.; Sun, X.; Boon, N.; Clauwaert, P. (2017). Ureolytic activity and its regulation in Vibrio campbellii and Vibrio harveyi in relation to nitrogen recovery from human urine. Environ. Sci. Technol. 51(22): 13335-13343. https://dx.doi.org/10.1021/acs.est.7b03829, more Eggermont, M.; Bossier, P.; Pande, G.S.J.; Delahaut, V.; Rayhan, A.M.; Gupta, N.; Islam, S.S.; Yumo, E.; Nevejan, N.; Sorgeloos, P.; Gomez-Gil, B.; Defoirdt, T. (2017). Isolation of Vibrionaceae from wild blue mussel (Mytilus edulis) adults and their impact on blue mussel larviculture. FEMS Microbiol. Ecol. 93(4): fix039. https://dx.doi.org/10.1093/femsec/fix039, more Suong, N.T.; Van Hao, N.; Van Sang, N.; Hung, N.D.; Tinh, N.T.N.; Phuoc, L.H.; Cuong, D.V.; Luan, N.T.; Phuong, D.V.; Thom, T.T.; Thao, P.H.; Bossier, P.; Sorgeloos, P.; Defoirdt, T. (2017). The impact of catecholamine sensing on the virulence of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease (AHPND). Aquaculture 470: 190-195. https://dx.doi.org/10.1016/j.aquaculture.2016.12.030, more Yang, Q.; Pande, G.; Wang, Z.; Lin, B.; Rubin, R.A.; Vora, G.J.; Defoirdt, T. (2017). Indole signalling and (micro)algal auxins decrease the virulence of Vibrio campbellii, a major pathogen of aquatic organisms. Environ. Microbiol. 19(5): 1987-2004. https://dx.doi.org/10.1111/1462-2920.13714, more Bossier, P.; De Schrijver, P.; Defoirdt, T.; Ruwandeepika, H.A.D.; Natrah, F.; Ekasari, J.; Toi, H.; Nhan, D.; Tinh, N.; Pande, G.; Karunasagar, I.; Van Stappen, G. (2016). Microbial community management in aquaculture. Procedia Food Science 6: 37-39. https://dx.doi.org/10.1016/j.profoo.2016.02.007, more Defoirdt, T. (2016). Implications of ecological niche differentiation in marine bacteria for microbial management in aquaculture to prevent bacterial disease. PLoS Pathog. 12(11): e1005843. https://dx.doi.org/10.1371/journal.ppat.1005843, more Gomez-Gil, B.; Roque, A.; Rotllant, G.; Romalde, L.; Doce, A.; Eggermont, M.; Defoirdt, T. (2016). Photobacterium sanguinicancri sp. nov. isolated from marine animals. Antonie van Leeuwenhoek 109(6): 817-825. https://dx.doi.org/10.1007/s10482-016-0681-x, more Baruah, K.; Ho Phuong Pham Duy Phong; Norouzitallab, P.; Defoirdt, T.; Bossier, P. (2015). The gnotobiotic brine shrimp (Artemia franciscana) model system reveals that the phenolic compound pyrogallol protects against infection through its prooxidant activity. Free Radic. Biol. Med. 89: 593-601. https://dx.doi.org/10.1016/j.freeradbiomed.2015.10.397, more LeRoux, F.; Wegner, K.; Baker-Austin, C.; Vezzulli, L.; Osorio, C.; Amaro, C.; Ritchie, J.; Defoirdt, T.; Destoumieux-Garzon, D.; Blokesch, M.; Mazel, D.; Jacq, A.; Cava, F.; Gram, L.; Wendling, C.; Strauch, E.; Kirschner, A.; Huehn, S. (2015). The emergence of Vibrio pathogens in Europe: ecology, evolution, and pathogenesis (Paris, 11-12th March 2015). Front. Microbiol. 6: 830. https://dx.doi.org/10.3389/fmicb.2015.00830, more Li, X.; Bossier, P.; Dierckens, K.; Laureau, S.; Defoirdt, T. (2015). Impact of mucin, bile salts and cholesterol on the virulence of Vibrio anguillarum towards gnotobiotic sea bass (Dicentrarchus labrax) larvae. Vet. Microbiol. 175(1): 44-49. https://dx.doi.org/10.1016/j.vetmic.2014.10.033, more Li, X.; Defoirdt, T.; Bossier, P. (2015). Relation between virulence of Vibrio anguillarum strains and response to the host factors mucin, bile salts and cholesterol. J. Appl. Microbiol. 119(1): 25-32. http://dx.doi.org/10.1111/jam.12813, more Ruwandeepika, H.A.D.; Karunasagar, I.; Bossier, P.; Defoirdt, T. (2015). Expression and quorum sensing regulation of type III secretion system genes of Vibrio harveyi during infection of gnotobiotic brine shrimp. PLoS One 10(12): e0143935. https://dx.doi.org/10.1371/journal.pone.0143935, more Vanmaele, S.; Defoirdt, T.; Cleenwerck, I.; De Vos, P.; Bossier, P. (2015). Characterization of the virulence of Harveyi clade vibrios isolated from a shrimp hatchery in vitro and in vivo, in a brine shrimp (Artemia franciscana) model system. Aquaculture 435: 28-32. dx.doi.org/10.1016/j.aquaculture.2014.09.015, more Yang, Q.; Defoirdt, T. (2015). Quorum sensing positively regulates flagellar motility in pathogenic Vibrio harveyi. Environ. Microbiol. 17(4): 960-968. https://dx.doi.org/10.1111/1462-2920.12420, more De Schryver, P.; Defoirdt, T.; Sorgeloos, P. (2014). Early mortality syndrome outbreaks: a microbial management issue in shrimp farming? PLoS Pathog. 10(4): -. dx.doi.org/10.1371/journal.ppat.1003919, more Eggermont, M.; Tamanji, A.; Nevejan, N.; Bossier, P.; Sorgeloos, P.; Defoirdt, T. (2014). Stimulation of heterotrophic bacteria associated with wild-caught blue mussel (Mytilus edulis) adults results in mass mortality. Aquaculture 431: 136-138. dx.doi.org/10.1016/j.aquaculture.2014.01.014, more Li, X.; Yang, Q.; Dierckens, K.; Milton, L; Defoirdt, T. (2014). RpoS and indole signaling control the virulence of Vibrio anguillarum towards gnotobiotic sea bass (Dicentrarchus labrax) larvae. PLoS One 9(10): -. dx.doi.org/10.1371/journal.pone.0111801, more Li, X.; Defoirdt, T.; Yang, Q.; Laureau, S.; Bossier, P.; Dierckens, K. (2014). Host-induced increase in larval sea bass mortality in a gnotobiotic challenge test with Vibrio anguillarum. Dis. Aquat. Org. 108(3): 211-216. dx.doi.org/10.3354/dao02722, more Niu, Y.; Defoirdt, T.; Baruah, K.; Van de Wiele, T.; Dong, L; Bossier, P. (2014). Bacillus sp. LT3 improves the survival of gnotobiotic brine shrimp (Artemia franciscana) larvae challenged with Vibrio campbellii by enhancing the innate immune response and by decreasing the activity of shrimp-associated vibrios. Vet. Microbiol. 173(3-4): 279-288. dx.doi.org/10.1016/j.vetmic.2014.08.007, more Yang, Q.; Anh, N.D.Q.; Bossier, P.; Defoirdt, T. (2014). Norepinephrine and dopamine increase motility, biofilm formation, and virulence of Vibrio harveyi. Front. Microbiol. 5: 12 pp. https://dx.doi.org/10.3389/fmicb.2014.00584, more Defoirdt, T. (2013). Virulence mechanisms of bacterial aquaculture pathogens and antivirulence therapy for aquaculture. Reviews in Aquaculture 6(2): 100-114. https://dx.doi.org/10.1111/raq.12030, more Defoirdt, T.; Pande, G.; Baruah, K.; Bossier, P. (2013). The apparent quorum-sensing inhibitory activity of pyrogallol is a side effect of peroxide production. Antimicrob. Agents Chemother. 57(6): 2870-2873. https://dx.doi.org/10.1128/AAC.00401-13, more Pande, G.; Natrah, F.M.I.; Sorgeloos, P.; Bossier, P.; Defoirdt, T. (2013). The Vibrio campbellii quorum sensing signals have a different impact on virulence of the bacterium towards different crustacean hosts. Vet. Microbiol. 167(3-4): 540-545. https://dx.doi.org/10.1016/j.vetmic.2013.08.021, more Vadstein, O.; Bergh, O.; Gatesoupe, F.J.; Galindo-Villegas, J.; Mulero, V.; Picchietti, S.; Scapigliati, G.; Makridis, P.; Olsen, Y.; Dierckens, K.; Defoirdt, T.; Boon, N.; De Schryver, P.; Bossier, P. (2013). Microbiology and immunology of fish larvae. Reviews in Aquaculture 5(S1): S1-S25. dx.doi.org/10.1111/j.1753-5131.2012.01082.x, more Vanmaele, S.; Defoirdt, T.; Bossier, P. (2013). Immunostimulation through the eyes of gnotobiotic Artemia franciscana. Fish Shellfish Immunol. 34(6): 1744-1744. https://dx.doi.org/10.1016/j.fsi.2013.03.332, more Asanka Gunasekara, R.A.Y.S.; Defoirdt, T.; Rekecki, A.; Decostere, A.; Cornelissen, M.; Sorgeloos, P.; Bossier, P.; Van Den Broeck, W. (2012). Light and transmission electron microscopy of Vibrio campbellii infection in gnotobiotic Artemia franciscana and protection offered by a yeast mutant with elevated cell wall glucan. Vet. Microbiol. 158(3-4): 337-343. http://dx.doi.org/10.1016/j.vetmic.2012.02.025, more Defoirdt, T.; Benneche, T.; Brackman, G.; Coenye, T.; Sorgeloos, P.; Scheie, A. (2012). A quorum sensing-disrupting brominated thiophenone with a promising therapeutic potential to treat luminescent vibriosis. PLoS One 7(7): e41788. dx.doi.org/10.1371/journal.pone.0041788, more Defoirdt, T.; Sorgeloos, P. (2012). Monitoring of Vibrio harveyi quorum sensing activity in real time during infection of brine shrimp larvae. ISME J. 6(12): 2314-2319. dx.doi.org/10.1038/ismej.2012.58, more Natrah, F.M.I.; Alam, M.I.; Pawar, S.; Harzevili, A.S.; Nevejan, N.; Boon, N.; Sorgeloos, P.; Bossier, P.; Defoirdt, T. (2012). The impact of quorum sensing on the virulence of Aeromonas hydrophila and Aeromonas salmonicida towards burbot (Lota lota L.) larvae. Vet. Microbiol. 159(1-2): 77-82. https://dx.doi.org/10.1016/j.vetmic.2012.03.014, more Niu, Y.; Defoirdt, T.; Rekecki, A.; De Schryver, P.; Van Den Broeck, W.; Dong, S.; Sorgeloos, P.; Boon, N.; Bossier, P. (2012). A method for the specific detection of resident bacteria in brine shrimp larvae. J. microbiol. methods 89(1): 33-37. https://dx.doi.org/10.1016/j.mimet.2012.02.004, more Ruwandeepika, H.; Jayaweera, T.; Bhowmick, P.; Karunasagar, I.; Bossier, P.; Defoirdt, T. (2012). Pathogenesis, virulence factors and virulence regulation of vibrios belonging to the Harveyi clade. Reviews in Aquaculture 4(2): 59-74. https://dx.doi.org/10.1111/j.1753-5131.2012.01061.x, more Defoirdt, T.; Thanh, L.D.; Van Delsen, B.; De Schryver, P.; Sorgeloos, P.; Boon, N.; Bossier, P. (2011). N-acylhomoserine lactone-degrading Bacillus strains isolated from aquaculture animals. Aquaculture 311(1-4): 258-260. https://dx.doi.org/10.1016/j.aquaculture.2010.11.046, more Defoirdt, T.; Sorgeloos, P.; Bossier, P. (2011). Alternatives to antibiotics for the control of bacterial disease in aquaculture. Curr. Opin. Microbiol. 14(3): 251-258. https://dx.doi.org/10.1016/j.mib.2011.03.004, more Natrah, F.M.I.; Ruwandeepika, H.A.D.; Pawar, S.; Karunasagar, I.; Sorgeloos, P.; Bossier, P.; Defoirdt, T. (2011). Regulation of virulence factors by quorum sensing in Vibrio harveyi. Vet. Microbiol. 154(1-2): 124-129. https://dx.doi.org/10.1016/j.vetmic.2011.06.024, more Natrah, F.M.I.; Kenmegne, M.M.; Wiyoto, W.; Sorgeloos, P.; Bossier, P.; Defoirdt, T. (2011). Effects of micro-algae commonly used in aquaculture on acyl-homoserine lactone quorum sensing. Aquaculture 317(1-4): 53-57. https://dx.doi.org/10.1016/j.aquaculture.2011.04.038, more Natrah, F.M.I.; Defoirdt, T.; Sorgeloos, P.; Bossier, P. (2011). Disruption of bacterial cell-to-cell communication by marine organisms and its relevance to aquaculture. Mar. Biotechnol. 13(2): 109-126. dx.doi.org/10.1007/s10126-010-9346-3, more Ruwandeepika, H.; Defoirdt, T.; Bhowmick, P.; Karunasagar, I.; Bossier, P. (2011). Expression of virulence genes in luminescent and nonluminescent isogenic vibrios and virulence towards gnotobiotic brine shrimp (Artemia franciscana). J. Appl. Microbiol. 110(2): 399-406. dx.doi.org/10.1111/j.1365-2672.2010.04892.x, more Ruwandeepika, H.; Bhowmick, P.; Karunasagar, I.; Bossier, P.; Defoirdt, T. (2011). Quorum sensing regulation of virulence gene expression in Vibrio harveyi in vitro and in vivo during infection of gnotobiotic brine shrimp larvae. Environmental Microbiology Reports 3(5): 597-602. https://dx.doi.org/10.1111/j.1758-2229.2011.00268.x, more Ruwandeepika, H.; Defoirdt, T.; Bhowmick, P.; Karunasagar, I.; Karunasagar, I.; Bossier, P. (2011). In vitro and in vivo expression of virulence genes in Vibrio isolates belonging to the Harveyi clade in relation to their virulence towards gnotobiotic brine shrimp (Artemia franciscana). Environ. Microbiol. 13(2): 506-517. http://dx.doi.org/10.1111/j.1462-2920.2010.02354.x, more Crab, R.; Lambert, A.; Defoirdt, T.; Bossier, P.; Verstraete, W. (2010). The application of bioflocs technology to protect brine shrimp (Artemia franciscana) from pathogenic Vibrio harveyi. J. Appl. Microbiol. 109(5): 1643-1649. dx.doi.org/10.1111/j.1365-2672.2010.04791.x, more Defoirdt, T.; Ruwandeepika, H.; Karunasagar, I.; Boon, N.; Bossier, P. (2010). Quorum sensing negatively regulates chitinase in Vibrio harveyi. Environmental Microbiology Reports 2(1): 44-49. https://dx.doi.org/10.1111/j.1758-2229.2009.00043.x, more Liu, Y.; De Schryver, P.; Van Delsen, B.; Maignien, L.; Boon, N.; Sorgeloos, P.; Verstraete, W.; Bossier, P.; Defoirdt, T. (2010). PHB-degrading bacteria isolated from the gastrointestinal tract of aquatic animals as protective actors against luminescent vibriosis. FEMS Microbiol. Ecol. 74(1): 196-204. dx.doi.org/10.1111/j.1574-6941.2010.00926.x, more Dang, T.V.C.; Nguyen, V.H.; Dierckens, K.; Defoirdt, T.; Boon, N.; Sorgeloos, P.; Bossier, P. (2009). Novel approach of using homoserine lactone-degrading and poly-beta-hydroxybutyrate-accumulating bacteria to protect Artemia from the pathogenic effects of Vibrio harveyi. Aquaculture 291(1-2): 23-30. dx.doi.org/10.1016/j.aquaculture.2009.03.009, more Phuoc, L.H.; Defoirdt, T.; Sorgeloos, P.; Bossier, P. (2009). Virulence of luminescent and non-luminescent isogenic vibrios towards gnotobiotic Artemia franciscana larvae and specific pathogen-free Litopenaeus vannamei shrimp. J. Appl. Microbiol. 106(4): 1388-1396. dx.doi.org/10.1111/j.1365-2672.2008.04107.x, more Qi, Z.; Dierckens, K.; Defoirdt, T.; Sorgeloos, P.; Boon, N.; Bao, Z.; Bossier, P. (2009). Effects of feeding regime and probionts on the diverting microbial communities in rotifer Brachionus culture. Aquacult. Int. 17(4): 303-315. dx.doi.org/10.1007/s10499-008-9202-x, more Qi, Z.; Dierckens, K.; Defoirdt, T.; Sorgeloos, P.; Boon, N.; Bao, Z.; Bossier, P. (2009). Analysis of the evolution of microbial communities associated with different cultures of rotifer strains belonging to different cryptic species of the Brachionus plicatilis species. Aquaculture 292(1-2): 23-29. dx.doi.org/10.1016/j.aquaculture.2009.03.030, more Sung, Y.; Dhaene, T.; Defoirdt, T.; Boon, N.; MacRae, T.; Sorgeloos, P.; Bossier, P. (2009). Ingestion of bacteria overproducing DnaK attenuates Vibrio infection of Artemia franciscana larvae. Cell Stress Chap. 14(6): 603-609. https://dx.doi.org/10.1007/s12192-009-0112-2, more Brackman, G.; Defoirdt, T.; Miyamoto, C.; Bossier, P.; Van Calenbergh, S.; Nelis, H.J.; Coenye, T. (2008). Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR. BMC Microbiol. 8. dx.doi.org/10.1186/1471-2180-8-149, more De Schryver, P.; Crab, R.; Defoirdt, T.; Boon, N.; Verstraete, W. (2008). The basics of bio-flocs technology: the added value for aquaculture. Aquaculture 277(3-4): 125-137. dx.doi.org/10.1016/j.aquaculture.2008.02.019, more Defoirdt, T.; Boon, N.; Sorgeloos, P.; Verstraete, W.; Bossier, P. (2008). Quorum sensing and quorum quenching in Vibrio harveyi: lessons learned from in vivo work. ISME J. 2(1): 19-26. dx.doi.org/10.1038/ismej.2007.92, more Defoirdt, T.; Verstraete, W.; Bossier, P. (2008). Luminescence, virulence and quorum sensing signal production by pathogenic Vibrio campbellii and Vibrio harveyi isolates. J. Appl. Microbiol. 104(5): 1480-1487. dx.doi.org/10.1111/j.1365-2672.2007.03672.x, more Crab, R.; Avnimelech, Y.; Defoirdt, T.; Bossier, P.; Verstraete, W. (2007). Nitrogen removal techniques in aquaculture for a sustainable production. Aquaculture 270(1-4): 1-14. dx.doi.org/10.1016/j.aquaculture.2007.05.006, more Defoirdt, T.; Boon, N.; Sorgeloos, P.; Verstraete, W.; Bossier, P. (2007). Alternatives to antibiotics to control bacterial infections: luminescent vibriosis in aquaculture as an example. Trends Biotechnol. 25(10): 472-479. dx.doi.org/10.1016/j.tibtech.2007.08.001, more Defoirdt, T.; Miyamoto, C.M.; Wood, T.K.; Meighen, E.A.; Sorgeloos, P.; Verstraete, W.; Bossier, P. (2007). The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding activity of the transcriptional regulator protein luxR. Environ. Microbiol. 9(10): 2486-2495. dx.doi.org/10.1111/j.1462-2920.2007.01367.x, more Defoirdt, T.; Halet, D.; Vervaeren, H.; Boon, N.; Van de Wiele, T.; Sorgeloos, P.; Bossier, P.; Verstraete, W. (2007). The bacterial storage compound poly-ß-hydroxybutyrate protects Artemia franciscana from pathogenic Vibrio campbellii. Environ. Microbiol. 9(2): 445-452. http://dx.doi.org/10.1111/j.1462-2920.2006.01161.x, more Halet, D.; Defoirdt, T.; Van Damme, P.; Vervaeren, H.; Forrez, I.; Van de Wiele, T.; Boon, N.; Sorgeloos, P.; Bossier, P.; Verstraete, W. (2007). Poly-ß-hydroxybutyrate-accumulating bacteria protect gnotobiotic Artemia franciscana from pathogenic Vibrio campbellii. FEMS Microbiol. Ecol. 60(3): 363-369, more Defoirdt, T.; Halet, D.; Sorgeloos, P.; Bossier, P.; Verstraete, W. (2006). Short-chain fatty acids protect gnotobiotic Artemia franciscana from pathogenic Vibrio campbellii. Aquaculture 261(2): 804-808. dx.doi.org/10.1016/j.aquaculture.2006.06.038, more Defoirdt, T.; Crab, R.; Wood, T.K.; Sorgeloos, P.; Verstraete, W.; Bossier, P. (2006). Quorum sensing-disrupting brominated furanones protect the gnotobiotic brine shrimp Artemia franciscana from pathogenic Vibrio harveyi, Vibrio campbellii, and Vibrio parahaemolyticus isolates. Appl. Environ. Microbiol. 72(9): 6419-6423. dx.doi.org/10.1128/AEM.00753-06, more Defoirdt, T.; Bossier, P.; Sorgeloos, P.; Verstraete, W. (2005). The impact of mutations in the quorum sensing systems of Aeromonas hydrophila, Vibrio anguillarum and Vibrio harveyi on their virulence towards gnotobiotically cultured Artemia franciscana. Environ. Microbiol. 7(8): 1239-1247. https://dx.doi.org/10.1111/j.1462-2920.2005.00807.x, more Defoirdt, T.; Boon, N.; Bossier, P.; Verstraete, W. (2004). Disruption of bacterial quorum sensing: an unexplored strategy to fight infections in aquaculture. Aquaculture 240(1-4): 69-88. dx.doi.org/10.1016/j.aquaculture.2004.06.031, more Peer reviewed publication [show] Kaur-Kahlon, G.; Kumar, B.K.; Ruwandeepika, H.A.D.; Defoirdt, T.; Karunasagar, I. (2021). Quorum sensing regulation of virulence gene expression in Vibrio harveyi during its interaction with marine diatom Skeletonema marinoi. Journal of Pure and Applied Microbiology 15(4): 2507-2519. https://dx.doi.org/10.22207/JPAM.15.4.78, more Abstracts (6) [show] Heyse, J.; Props, R.; Kongnuan, P.; De Schryver, P.; Rombaut, G.; Defoirdt, T.; Boon, N. (2021). Microbiomes of live feed products have an important contribution to the rearing water microbiomes in Litopenaeus vannamei larviculture, in: Mees, J. et al. Book of abstracts – VLIZ Marine Science Day, Online event 3 March 2021. VLIZ Special Publication, 85: pp. 69, more Vanmaele, S.; Defoirdt, T.; Bossier, P. (2012). Aquaculture and immunostimulation through the eyes of Artemia, in: Mees, J. et al. (Ed.) Book of abstracts - VLIZ Young Marine Scientists' Day. Brugge, Belgium, 24 February 2012. VLIZ Special Publication, 55: pp. 104, more Natrah, F.M.I.; Defoirdt, T.; Mardel, M.; Wiyoto, W.; Sorgeloos, P.; Bossier, P. (2011). Quorum sensing inhibitors from micro-algae commonly used in aquaculture, in: Mees, J. et al. (Ed.) VLIZ Young Marine Scientists' Day, Brugge, Belgium 25 February 2011: book of abstracts. pp. 58, more Plovie, A.; Nevejan, N.M.; Defoirdt, T.; Boon, N.; Bossier, P. (2011). Quorum sensing-interference to reduce mortality during blue mussel (Mytilus edulis) larviculture, in: Mees, J. et al. (Ed.) VLIZ Young Marine Scientists' Day, Brugge, Belgium 25 February 2011: book of abstracts. pp. 65, more Defoirdt, T.; Miyamoto, C.M.; Wood, T.K.; Meighen, E.A.; Sorgeloos, P.; Verstraete, W.; Bossier, P. (2009). The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3- butyl-2(5H)-furanone disrupts quorum sensing in Vibrio harveyi by decreasing the DNA-binding activity of the master regulator luxR, in: Mees, J. et al. (Ed.) Book of abstracts: an overview of marine research in Belgium anno 2009. 10th VLIZ Young Scientists' Day. Special edition at the occasion of 10 years VLIZ. VLIZ Special Publication, 43: pp. 48, more Defoirdt, T.; Halet, D.; Sorgeloos, P.; Bossier, P.; Verstraete, W. (2007). The bacterial storage compound PHB protects Artemia franciscana from pathogenic Vibrio campbellii, in: Mees, J. et al. (Ed.) VLIZ Young Scientists' Day, Brugge, Belgium 2 March 2007: book of abstracts. VLIZ Special Publication, 39: pp. 30, more Thesis (co-)promotor [show] Goeteyn, T. (2020). Opportunities for management of Vibrio pathogens in aquaculture. Ir Thesis. Universiteit Gent - Faculteit Bio-ingenieurswetenschappen: Gent. 73 pp., more All data in the Integrated Marine Information System (IMIS) is subject to the VLIZ privacy policy  Top | Publications | Project