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Fish collagen: extraction, characterization, and applications for biomaterials engineering
Jafari, H.; Lista, A.; Siekapen, M.M.; Ghaffari-Bohlouli, P.; Nie, L.; Alimoradi, H.; Shavandi, A. (2020). Fish collagen: extraction, characterization, and applications for biomaterials engineering. Polymers 12(10): 2230. https://hdl.handle.net/10.3390/polym12102230
In: Polymers. MDPI AG: Basel. e-ISSN 2073-4360, more
Peer reviewed article  

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Keyword
    Marine/Coastal
Author keywords
    fish collagen; deep eutectic solvent; medical applications; collagen extraction

Authors  Top 
  • Jafari, H., more
  • Lista, A.
  • Siekapen, M.M.
  • Ghaffari-Bohlouli, P.
  • Nie, L.
  • Alimoradi, H.
  • Shavandi, A., more

Abstract
    The utilization of marine-based collagen is growing fast due to its unique properties in comparison with mammalian-based collagen such as no risk of transmitting diseases, a lack of religious constraints, a cost-effective process, low molecular weight, biocompatibility, and its easy absorption by the human body. This article presents an overview of the recent studies from 2014 to 2020 conducted on collagen extraction from marine-based materials, in particular fish by-products. The fish collagen structure, extraction methods, characterization, and biomedical applications are presented. More specifically, acetic acid and deep eutectic solvent (DES) extraction methods for marine collagen isolation are described and compared. In addition, the effect of the extraction parameters (temperature, acid concentration, extraction time, solid-to-liquid ratio) on the yield of collagen is investigated. Moreover, biomaterials engineering and therapeutic applications of marine collagen have been summarized.

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