IMIS | Lifewatch regional portal

You are here

IMIS

[ report an error in this record ]basket (0): add | show Print this page

Daminin, a bioactive pyrrole alkaloid from the Mediterranean sponge Axinella damicornis
Aiello, A.; D'Esposito, M.; Fattorusso, E.; Menna, M.; Müller, W.E.G.; Perovic-Ottstadt, S.; Tsuruta, H.; Gulder, T.A.M.; Bringmann, G. (2005). Daminin, a bioactive pyrrole alkaloid from the Mediterranean sponge Axinella damicornis. Tetrahedron 61(30): 7266-7270. https://dx.doi.org/10.1016/j.tet.2005.05.025
In: Tetrahedron. Pergamon Press: New York; Oxford; Paris; Frankfurt. ISSN 0040-4020; e-ISSN 1464-5416, more
Peer reviewed article  

Available in  Authors | Dataset 

Keywords
    Axinella damicornis (Esper, 1794) [WoRMS]
    Marine/Coastal

Authors  Top | Dataset 
  • Aiello, A.
  • D'Esposito, M.
  • Fattorusso, E.
  • Menna, M.
  • Müller, W.E.G.
  • Perovic-Ottstadt, S.
  • Tsuruta, H.
  • Gulder, T.A.M.
  • Bringmann, G.

Abstract
    The isolation and characterization of the known pyrrole alkaloid agelongine (6) and of the new natural product daminin (7), the bromine-free analogue of 6, from a specimen of the marine sponge Axinella damicornis is described. Compound 7 showed significant neuroprotective properties. Moreover, for the supply of sufficient material for future medicinal investigations, a short total synthesis of 7 was developed.

Dataset
  • CorMedNet- Distribution and demographic data of habitat-forming invertebrate species from Mediterranean coralligenous assemblages between 1882 and 2019., more

All data in the Integrated Marine Information System (IMIS) is subject to the VLIZ privacy policy Top | Authors | Dataset